研究業績

研究業績

2022

  1. Nakashima M, Utsunomiya A, Watanabe T, Horie R, Uchimaru K. The oncogenic driving force of CD30 signaling-induced chromosomal instability in adult T-cell leukemia/lymphoma. Cancer Sci. 2022 Dec 21. doi: 10.1111/cas.15706. Online ahead of print.PMID: 36541483 
  2. Imaizumi Y, Iwanaga M, Nosaka K, Ishitsuka K, Ishizawa K, Ito S, Amano M, Ishida T, Uike N, Utsunomiya A, Ohshima K, Tanaka J, Tokura Y, Tobinai K, Watanabe T, Uchimaru K, Tsukasaki K. Validation of the iATL-PI prognostic index in therapeutic decision-making for patients with smoldering and chronic ATL: a multicenter study. Int J Hematol. 2023 Feb;117(2):206-215. doi: 10.1007/s12185-022-03473-y. Epub 2022 Oct 29.PMID: 36308678
  3. Tanaka Y, Sato T, Yagishita N, Yamauchi J, Araya N, Aratani S, Takahashi K, Kunitomo Y, Nagasaka M, Kanda Y, Uchimaru K, Morio T, Yamano Y. Potential role of HTLV-1 Tax-specific cytotoxic t lymphocytes expressing a unique t-cell receptor to promote inflammation of the central nervous system in myelopathy associated with HTLV-1. Front Immunol. 2022 Aug 23;13:993025. doi: 10.3389/fimmu.2022.993025. eCollection 2022. PMID: 36081501
  4. Fuji S, Yasunaga JI, Watanabe E, Matsuoka M, Uchimaru K, Ishikawa J. Pseudo-progression of adult T-cell leukemia-lymphoma after cord blood transplantation. Fuji S, Yasunaga JI, Watanabe E, Matsuoka M, Uchimaru K, Ishikawa J. Haematologica. 2022 Jun 23. doi: 10.3324/ haematol. 2022.281175. Online ahead of print. PMID: 35734929
  5. Wada Y, Sato T, Hasegawa H, Matsudaira T, Nao N, Coler-Reilly ALG, Tasaka T, Yamauchi S, Okagawa T, Momose H, Tanio M, Kuramitsu M, Sasaki D, Matsumoto N, Yagishita N, Yamauchi J, Araya N, Tanabe K, Yamagishi M, Nakashima M, Nakahata S, Iha H, Ogata M, Muramatsu M, Imaizumi Y, Uchimaru K, Miyazaki Y, Konnai S, Yanagihara K, Morishita K, Watanabe T, Yamano Y, Saito M. RAISING is a high-performance method for identifying random transgene integration sites. Commun Biol. 2022 Jun 2;5(1):535. doi: 10.1038/s42003-022-03467-w. PMID: 35654946
  6. Kamoi K, Watanabe T, Uchimaru K, Okayama A, Kato S, Kawamata T, Kurozumi-Karube H, Horiguchi N, Zong Y, Yamano Y, Hamaguchi I, Nannya Y, Tojo A, Ohno-Matsui K. Updates on HTLV-1 Uveitis. Viruses. 2022 Apr 12;14(4):794. doi: 10.3390/v14040794. PMID: 35458524
  7. Takeda R, Yokoyama K, Fukuyama T, Kawamata T, Ito M, Yusa N, Kasajima R, Shimizu E, Ohno N, Uchimaru K, Yamaguchi R, Imoto S, Miyano S, Tojo A. Repeated Lineage Switches in an Elderly Case of Refractory B-Cell Acute Lymphoblastic Leukemia With MLL Gene Amplification: A Case Report and Literature Review. Front Oncol. 2022 Mar 23;12:799982. doi: 10.3389/fonc.2022.799982. eCollection 2022. PMID: 35402256
  8. Yamagishi M, Suzuki Y, Watanabe T, Uchimaru K. Clonal Selection and Evolution of HTLV-1-Infected Cells Driven by Genetic and Epigenetic Alteration. Viruses. 2022 Mar 12;14(3):587. doi: 10.3390/v14030587. PMID: 35336993
  9. Nakano K, Yokoyama K, Shin S, Uchida K, Tsuji K, Tanaka M, Uchimaru K, Watanabe T. Exploring New Functional Aspects of HTLV-1 RNA-Binding Protein Rex: How Does Rex Control Viral Replication?. Viruses. 2022 Feb 16;14(2):407. doi: 10.3390/v14020407. PMID: 35216000
  10. Nakano K, Karasawa N, Hashizume M, Tanaka Y, Ohsugi T, Uchimaru K, Watanabe T. Elucidation of the Mechanism of Host NMD Suppression by HTLV-1 Rex: Dissection of Rex to Identify the NMD Inhibitory Domain. Viruses. 2022 Feb 9;14(2):344. doi: 10.3390/v14020344. PMID: 35215946
  11. Kamoi K, Uchimaru K, Tojo A, Watanabe T, Ohno-Matsui K. HTLV-1 uveitis and Graves' disease presenting with sudden onset of blurred vision. Lancet. 2022 Jan 1;399(10319):60. doi: 10.1016/ S0140-6736(21)02442-9.PMID: 34973718 No abstract available.

2021

  1. Tan BJ, Sugata K, Reda O, Matsuo M, Uchiyama K, Miyazato P, Hahaut V, Yamagishi M, Uchimaru K, Suzuki Y, Ueno T, Suzushima H, Katsuya H, Tokunaga M, Uchiyama Y, Nakamura H, Sueoka E, Utsunomiya A, Ono M, Satou Y. HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma. J Clin Invest.  2021 Dec 15;131(24):e150472. doi: 10.1172/JCI150472.
  2. Ito A, Nakano N, Tanaka T, Fuji S, Makiyama J, Inoue Y, Choi I, Nakamae H, Nagafuji K, Takase K, Machida S, Takahashi T, Sawayama Y, Kamimura T, Kato K, Kawakita T, Ogata M, Sakai R, Shiratori S, Uchimaru K, Inamoto Y, Utsunomiya A, Fukuda T. Improved survival of patients with aggressive ATL by increased use of allo-HCT: a prospective observational study. Blood Adv. 2021 Oct 26;5(20):4156-4166. doi: 10.1182/bloodadvances.2021004932. PMID: 34500464.
  3. Yamagishi M, Kubokawa M, Kuze Y, Suzuki A, Yokomizo A, Kobayashi S, Nakashima M, Makiyama J, Iwanaga M, Fukuda T, Watanabe T, Suzuki Y, Uchimaru K. Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma. Nat Commun. 2021 Aug 10;12(1):4821. doi: 10.1038/s41467-021-25101-9. PMID: 34376672
  4. Ito S, Iwanaga M, Nosaka K, Imaizumi Y, Ishitsuka K, Amano M, Utsunomiya A, Tokura Y, Watanabe T, Uchimaru K, Tsukasaki K; Collaborative Investigators. Epidemiology of adult T-cell leukemia-lymphoma in Japan: An updated analysis, 2012-2013. Cancer Sci. 2021 Oct;112(10):4346-4354. doi: 10.1111/cas.15097. Epub 2021 Aug 15. PMID: 34355480
  5. Kamoi K, Horiguchi N, Kurozumi-Karube H, Hamaguchi I, Yamano Y, Uchimaru K, Tojo A, Watanabe T, Ohno-Matsui K. Horizontal transmission of HTLV-1 causing uveitis. Lancet Infect Dis. 2021 Apr;21(4):578. doi: 10.1016/S1473-3099(21)00063-3. PMID: 33773136
  6. Nakashima M, Watanabe M, Nakano K, Uchimaru K, Horie R. Differentiation of Hodgkin lymphoma cells by reactive oxygen species and regulation by heme oxygenase-1 through HIF-1α. Cancer Sci. 2021 Mar 19. doi: 10.1111/cas.14890. Online ahead of print. PMID: 33738869
  7. Penova M, Kawaguchi S, Yasunaga JI, Kawaguchi T, Sato T, Takahashi M, Shimizu M, Saito M, Tsukasaki K, Nakagawa M, Takenouchi N, Hara H, Matsuura E, Nozuma S, Takashima H, Izumo S, Watanabe T, Uchimaru K, Iwanaga M, Utsunomiya A, Tabara Y, Paul R, Yamano Y, Matsuoka M, Matsuda F. Genome wide association study of HTLV-1-associated myelopathy/tropical spastic paraparesis in the Japanese population. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2004199118. doi: 10.1073/pnas.2004199118. PMID: 33649182
  8. Nakano K, Chihara Y, Kobayashi S, Iwanaga M, Utsunomiya A, Watanabe T, Uchimaru K. Overexpression of aberrant Wnt5a and its effect on acquisition of malignant phenotypes in adult T-cell leukemia/lymphoma (ATL) cells. Sci Rep. 2021 Feb 18;11(1):4114. doi: 10.1038/s41598-021-83613-2. PMID: 33603066

2020

  1. Mitsuhito Hirano, Koichi Kimura, Tomohiro Ishigaki, Masanori Nojima, Masao Daimon, Hiroyuki Morita, Katsu Takenaka, Boqing Xu, Naoko Sawada, Megumi Hirokawa, Issei Komuro, Takayuki Morisaki, Hiroshi Yotsuyanagi, Toyotaka Kawamata, Kazuaki Yokoyama, Takaaki Konuma, Seiko Kato, Hiroshi Yasui, Tokiko Nagamura-Inoue, Kaoru Uchimaru, Satoshi Takahashi, Yoichi Imai, Arinobu Tojo.  High Prevalence of Left Ventricular Non-Compaction and Its Effect on Chemotherapy-Related Cardiac Dysfunction in Patients With Hematological Diseases. Circulation Journal . 2020 Oct 23, 84(11);1957 – 1964. MS ID:CJ-20-0344 - Publishing Schedule
  2. Kamoi K, Kato S, Uchimaru K, Tojo A, Ohno-Matsui K. Frosted branch angiitis after allogeneic haematopoietic stem cell transplantation in adult T-cell leukaemia-lymphoma. Lancet Haematol. 2020 Oct;7(10):e772. doi: 10.1016/S2352-3026(20)30226-X.
  3. Imaizumi Y, Iwanaga M, Nosaka K, Ishitsuka K, Ishizawa K, Ito S, Amano M, Ishida T, Uike N, Utsunomiya A, Ohshima K, Tanaka J, Tokura Y, Tobinai K, Watanabe T, Uchimaru K, Tsukasaki K; for collaborative investigators. Prognosis of patients with adult T-cell leukemia/lymphoma in Japan: A nationwide hospital-based study. Cancer Sci. 2020 Sep 25. doi: 10.1111/cas.14658. Online ahead of print.
  4. Okuma K, Kuramitsu M, Niwa T, Taniguchi T, Masaki Y, Ueda G, Matsumoto C, Sobata R, Sagara U, Nakamura H, Satake M, Miura K, Fuchi N, Masuzaki H, Okayama A, Umeki K, Yamano Y, Sato T, Iwanaga M, Uchimaru K, Nakashima M, Utsunomiya A, Kubota R, Ishitsuka K, Hasegawa H, Sasaki D, Koh KR, Taki M, Nosaka K, Ogata M, Naruse I, Kaneko N, Okajima S, Tezuka K, Emi Ikebe ,Matsuoka S, Itabashi K, Saito S, Watanabe T, Hamaguchi I. Establishment of a novel diagnostic test algorithm for human T-cell leukemia virus type 1 infection with line immunoassay replacement of western blotting: a collaborative study for performance evaluation of diagnostic assays in Japan. Retrovirology. 2020 Aug 24;17(1):26.  doi: 10.1186/s12977-020-00534-0.
  5. Saito M, Hasegawa H, Yamauchi S, Nakagawa S, Sasaki D, Nao N, Tanio M, Wada Y, Matsudaira T, Momose H, Kuramitsu M, Yamagishi M, Nakashima M, Nakahata S, Iha H, Ogata M, Imaizumi Y, Uchimaru K, Morishita K, Watanabe T, Miyazaki Y, Yanagihara K. A high-throughput detection method for the clonality of Human T-cell leukemia virus type-1-infected cells in vivo. Int J Hematol. 2020 Sep;112(3):300-306.  doi: 10.1007/s12185-020-02935-5.  Epub 2020 Jul 29.
  6. Nagasaka M, Yamagishi M, Yagishita N, Araya N, Kobayashi S, Makiyama J, Kubokawa M, Yamauchi J, Hasegawa D, Coler-Reilly A, Tsutsumi S, Uemura Y, Arai A, Takata A, Inoue E, Hasegawa Y, Watanabe T, Suzuki Y, Uchimaru K, Sato T, Yamano Y. Mortality and risk of progression to adult T-cell leukemia/lymphoma in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. Proc. Natl. Acad. Sci. U S A. 2020 May 26;117(21):11685-11691. doi: 10.1073/ pnas.1920346117.Epub 2020 May 11.  
  7. Ikebe E, Matsuoka S, Tezuka K, Kuramitsu M, Okuma K, Nakashima M, Kobayashi S, Makiyama J, Yamagishi M, Oyadomari S, Uchimaru K, Hamaguchi I. Activation of PERK-ATF4-CHOP pathway as a novel therapeutic approach for efficient elimination of HTLV-1-infected cells. Blood Adv.2020 May 12;4(9):1845-1858. doi: 10.1182/bloodadvances.2019001139.
  8. Kazuo Itabashi, Tokuo Miyazawa, Akihiko Sekizawa, Akifumi Tokita, Shigeru Saito, Hiroyuki Moriuchi, Yasuhito Nerome, Kaoru Uchimaru, Toshiki Watanabe. A Nationwide Antenatal Human T-Cell Leukemia Virus Type-1 Antibody Screening in Japan. Front. Microbiol. 09 April 2020
  9. Kamoi K, Okayama A, Izumo S, Hamaguchi I, Uchimaru K, Tojo A, Watanabe T, Ohno-Matsui K. Tackling HTLV-1 infection in ophthalmology: a nationwide survey of ophthalmic care in an endemic country, Japan. Br J Ophthalmol. 2020 Mar 9. pii: bjophthalmol-2019-315675. doi: 10.1136/ bjophthalmol-2019-315675. [Epub ahead of print]
  10. Hirose L, Hiramoto T, Tian Y, Kohara H, Kobayashi S, Nagai E, Denda T, Tanaka Y, Ota Y, Jiyuan L, Miyamoto S, Miura Y, Hijikata Y, Soda Y, Inoue T, Okahara N, Itoh T, Sasaki E, Tojo A, Uchimaru K, Tani K. A pilot study to establish human T-cell leukemia virus type 1 (HTLV-1) carrier model using common marmoset (Callithrix jacchus).  J Med Primatol. 2020 Apr;49(2):86-94. doi: 10.1111/jmp.12454. Epub 2020 Jan 12.
  11. Takeda R, Ishigaki T, Ohno N, Yokoyama K, Kawamata T, Fukuyama T, Araya N, Yamano Y, Uchimaru K, Tojo A. Immunophenotypic analysis of cerebrospinal fluid reveals concurrent development of ATL in the CNS of a HAM/TSP patient. Int J Hematol. 2020 Jan 13. doi: 10.1007/s12185-019-02815-7. [Epub ahead of print]
  12. Hijikata Y, Yokoyama K, Yokoyama N, Matsubara Y, Shimizu E, Nakashima M, Yamagishi M, Ota Y, Lim LA, Yamaguchi R, Ito M, Tanaka Y, Denda T, Tani K, Yotsuyanagi H, Imoto S, Miyano S, Uchimaru K, Tojo A. Successful Clinical Sequencing by Molecular Tumor Board in an Elderly Patient With Refractory Sézary Syndrome. JCO Precision Oncology, 4, 534-560, 2020.

2019

  1. Fuji S, Kurosawa S, Inamoto Y, Murata T, Utsunomiya A, Uchimaru K, Yamasaki S, Inoue Y, Moriuchi Y, Choi I, Ogata M, Hidaka M, Yamaguchi T, Fukuda T. A decision analysis comparing unrelated bone marrow transplantation and cord blood transplantation in patients with aggressive adult T-cell leukemia-lymphoma. Int J Hematol. 2020 Mar;111(3):427-433. doi: 10.1007/s12185-019-02777-w. Epub 2019 Nov 7.
  2. Yamagishi M* (*corresponding author), Hori M, Fujikawa D, Ohsugi T, Honma D, Adachi N, Katano H, Hishima T, Kobayashi S, Nakano K, Nakashima M, Iwanaga M, Utsunomiya A, Tanaka Y, Okada S, Tsukasaki K, Tobinai K, Araki K, Watanabe T, Uchimaru K. Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas. Cell Rep. 2019 Nov 19;29(8):2321-2337.e7
  3. Katsuya H, Islam S, Tan BJY, Ito J, Miyazato P, Matsuo M, Inada Y, Iwase SC, Uchiyama Y, Hata H, Sato T, Yagishita N, Araya N, Ueno T, Nosaka K, Tokunaga M, Yamagishi M, Watanabe T, Uchimaru K, Fujisawa JI, Utsunomiya A, Yamano Y, Satou Y. The Nature of the HTLV-1 Provirus in Naturally Infected Individuals Analyzed by the Viral DNA-Capture-Seq Approach. Cell Rep. 2019 Oct 15;29(3):724-735.e4. doi: 10.1016/j.celrep.2019.09.016.
  4. Takeda R, Yokoyama K, Kobayashi S, Kawamata T, Nakamura S, Fukuyama T, Ito M, Yusa N, Shimizu E, Ohno N, Yamaguchi R, Imoto S, Miyano S, Uchimaru K, Tojo A. An Unusually Short Latent Period of Therapy-Related Myeloid Neoplasm Harboring a Rare MLL-EP300 Rearrangement: Case Report and Literature Review. Case Rep Hematol. 2019 Oct 2;2019:4532434. doi: 10.1155/2019/4532434. eCollection 2019.
  5. Nakano K, Iwanaga M, Utsunomiya A, Uchimaru K, and Watanabe T. (2019). Functional analysis of aberrantly spliced caspase8 variants in adult T-cell leukemia cells.  Mol Cancer Res. 2019 Dec;17(12):2522-2536. doi: 10.1158/1541-7786.MCR-19-0313. Epub 2019 Oct 8.
  6. Ishikawa M, Osaki M, Yamagishi M, Onuma K, Ito H, Okada F, Endo H. Correlation of two distinct metastasis-associated proteins, MTA1 and S100A4, in angiogenesis for promoting tumor growth. Oncogene. 2019 Feb 11. doi: 10.1038/s41388-019-0748-z. 
  7. Makiyama J, Kobayashi S, Watanabe E, Ishigaki T, Kawamata T, Nakashima M, Yamagishi M, Nakano K, Tojo A, Watanabe T, Uchimaru K. CD4+ CADM1+ cell percentage predicts disease progression in HTLV-1 carriers and indolent adult T-cell leukemia/lymphoma. Cancer Sci. 110: 3746-3753, 2019. doi: 10.1111/cas.14219.
  8. Takeda R, Yokoyama K, Ogawa M, Kawamata T, Fukuyama T, Kondoh K, Takei T, Nakamura S, Ito M, Yusa N, Shimizu E, Ohno N, Uchimaru K, Yamaguchi R, Imoto S, Miyano S, Tojo A. The first case of elderly TCF3-HLF-positive B-cell acute lymphoblastic leukemia. Leuk Lymphoma. 2019 Nov;60(11):2821-2824. doi: 10.1080/10428194.2019.1602267. Epub 2019 May 6. No abstract available.
  9. Kamoi K, Okayama A, Izumo S, Hamaguchi I, Uchimaru K, Tojo A, Ohno-Matsui K. Adult T-Cell Leukemia/Lymphoma-Related Ocular Manifestations: Analysis of the First Large-Scale Nationwide Survey. Front Microbiol. 2019 Jan 8;9:3240. doi: 10.3389/fmicb.2018.03240. eCollection 2018. PMID: 30671044
  10. Cook LB, Fuji S, Hermine O, Bazarbachi A, Ramos JC, Ratner L, Horwitz S, Fields P, Tanase A, Bumbea H, Cwynarski K, Taylor G, Waldmann TA, Bittencourt A, Marcais A, Suarez F, Sibon D, Phillips A, Lunning M, Farid R, Imaizumi Y, Choi I, Ishida T, Ishitsuka K, Fukushima T, Uchimaru K, Takaori-Kondo A, Tokura Y, Utsunomiya A, Matsuoka M, Tsukasaki K, Watanabe T. Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report. J Clin Oncol. 2019 Mar 10;37(8):677-687. doi: 10.1200/JCO.18.00501. Epub 2019 Jan 18.

2018

  1. Hirano M, Ota Y, Koibuchi T, Takei T, Takeda R, Kawamata T, Yokoyama K, Uchimaru K, Yotsuyanagi H, Imai Y, Tojo A. Nested polymerase chain reaction with specific primers for Mucorales in the serum of patients with hematological malignancies. Jpn J Infect Dis. 2019 May 23;72(3):196-198. doi: 10.7883/yoken.JJID.2018.379. Epub 2018 Dec 25.
  2. Kuramitsu M, Okuma K, Nakashima M, Sato T, Sasaki D, Hasegawa H, Umeki K, Kubota R, Sasada K, Sobata R, Matsumoto C, Kaneko N, Tezuka K, Matsuoka S, Utsunomiya A, Koh KR, Ogata M, Ishitsuka K, Taki M, Nosaka K, Uchimaru K, Iwanaga M, Sagara Y, Yamano Y, Okayama A, Miura K, Satake M, Saito S, Watanabe T, Hamaguchi I. Development of reference material with assigned value for human T-cell leukemia virus type 1 quantitative PCR in Japan. Microbiol Immunol. 2018 Oct;62(10):673-676. doi: 10.1111/1348-0421.12644.
  3. Yamagishi M, Fujikawa D, Watanabe T, Uchimaru K. HTLV-1-Mediated Epigenetic Pathway to Adult T-Cell Leukemia-Lymphoma. Front Microbiol. 2018 Jul 24;9:1686. doi: 10.3389/fmicb.2018.01686. eCollection 2018.
  4. Nakashima M, Yamochi T, Watanabe M, Uchimaru K, Utsunomiya A, Higashihara M, Watanabe T, Horie R. CD30 Characterizes Polylobated Lymphocytes and Disease Progression in HTLV-1-Infected Individuals. Clin Cancer Res. 2018 Nov 1;24(21):5445-5457. doi: 10.1158/1078-0432.CCR-18-0268. Epub 2018 Aug 1.
  5. Hirano M, Jimbo K, Ogawa M, Ochi K, Makiyama J, Kawamata T, Yokoyama K, Tanaka T, Inamoto Y, Yamano Y, Fukuda T, Uchimaru K, Imai Y, Tojo A. Chronic inflammatory demyelinating polyneuropathy in adult T-cell leukemia-lymphoma patients following allogeneic stem cell transplantation. Bone Marrow Transplant. 2018 Nov;53(11):1470-1473. doi: 10.1038/s41409-018-0202-9. Epub 2018 Jul 23.
  6. Nakashima M, Watanabe M, Uchimaru K, Horie R. Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling. Biol Cell. 2018 May;110(5):109-124. doi: 10.1111/boc. 201800002. Epub 2018 Mar 12.
  7. Sato T, Coler-Reilly ALG, Yagishita N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y, Yamano Y. Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy. N Engl J Med. 2018 Feb 8;378(6):529-538. doi: 10.1056/NEJMoa1704827. 
  8. Fuji S, Kurosawa S, Inamoto Y, Murata T, Utsunomiya A, Uchimaru K, Yamasaki S, Inoue Y, Moriuchi Y, Choi I, Ogata M, Hidaka M, Yamaguchi T, Fukuda T. Role of up-front allogeneic hematopoietic stem cell transplantation for patients with aggressive adult T-cell leukemia-lymphoma: a decision analysis. Bone Marrow Transplant. 2018 Jul;53(7):905-908. doi: 10.1038/s41409-017-0082-4. Epub 2018 Jan 25.
  9. Tanabe A, Nakano K, Nakakido M, Nagatoishi S, Tanaka Y, Tsumoto K, Uchimaru K, Watanabe T. Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery. Biochem Biophys Res Commun. 2018 Feb 5;496(2):614-620. doi: 10.1016/j.bbrc.2018.01.051. Epub 2018 Jan 9.
  10. Kobayashi-Ishihara M, Terahara K, Martinez JP, Yamagishi M, Iwabuchi R, Brander C, Ato M, Watanabe T, Meyerhans A, Tsunetsugu-Yokota Y. HIV LTR-driven antisense RNA by itself has regulatory function and may curtail virus reactivation from latency. Front. Microbiol. 9:1066, 2018 doi:10.3389/ fmicb.2018.01066, 
  11. Tanabe A, Nakano K, Nakakido M, Nagatoishi S, Tanaka Y, Tsumoto K, Uchimaru K, Watanabe T. (2018). Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery. Biochem Biophys Res Commun. 2018 Feb 5;496(2):614-620. doi: 10.1016/j.bbrc.2018.01.051. Epub 2018 Jan 9. PMID: 29330050

2017

  1. Miho Ogawa, Kazuaki Yokoyama, Mitsuhito Hirano, Koji Jimbo, Kiyosumi Ochi, Toyotaka Kawamata, Nobuhiro Ohno, Eigo Shimizu,Nozomi Yokoyama,Rui Yamaguchi,Seiya Imoto, Kaoru Uchimaru, Satoru Miyano,Yoichi Imai, Arinobu Tojo. Different Clonal Dynamics of Chronic Myeloid Leukaemia between Bone Marrow and the Central Nervous System. Journal: British Journal of Haematology. 2018 Dec;183(5):842-845. doi: 10.1111/bjh.15065. Epub 2017 Dec 19. 
  2. Kato T, Miyoshi H, Kobayashi S, Yoshida N, Imaizumi Y, Seto M, Uchimaru K, Miyazaki Y, Ohshima K. Clinicopathological analysis in PTCL-NOS with CADM1 expression. Virchows Arch. 2017 Nov;471(5):659-666. doi: 10.1007/s00428-017-2233-9. Epub 2017 Sep 22.
  3. Nosaka K, Iwanaga M, Imaizumi Y, Ishitsuka K, Ishizawa K, Ishida Y, Amano M, Ishida T, Uike N, Utsunomiya A, Ohshima K, Kawai K, Tanaka J, Tokura Y, Tobinai K, Watanabe T, Uchimaru K, Tsukasaki K. Epidemiological and clinical features of adult T-cell leukemia-lymphoma in Japan, 2010-2011: A nationwide survey. Cancer Sci2017 Dec;108(12):2478-2486.  doi: 10.1111/cas.13398. Epub 2017 Oct 8.
  4. Yasu T, Imai Y, Ohno N, Uchimaru K, Kurokawa Y, Tojo A. Hypersensitivity reaction to β-lactam antibiotics in patients with adult T-cell leukemia/lymphoma treated with mogamulizumab. Int J Clin Pharmacol Ther. 2017 Oct;55(10):807-810. doi: 10.5414/CP203066. 
  5. Ishihara Y, Tanaka Y, Kobayashi S, Kawamura K, Nakasone H, Gomyo A, Hayakawa J, Tamaki M, Akahoshi Y, Harada N, Kusuda M, Kameda K, Ugai T, Wada H, Sakamoto K, Sato M, Terasako-Saito K, Kikuchi M, Kimura SI, Tanihara A, Kako S, Uchimaru K, Kanda Y. A unique T cell receptor amino acid sequence selected by HTLV-I Tax301-309-specific cytotoxic T-cells in HLA-A24:02+ asymptomatic carriers and adult T-cell leukemia/lymphoma patients. J Virol. 2017 Sep 12;91(19). pii: e00974-17. doi: 10.1128/JVI.00974-17. Print 2017 Oct 1.
  6. Shimada N, Ohno N, Tanosaki R, Fuji S, Suzuki Y, Yuji K, Uchimaru K, Tojo A. Therapy-related Acute Myeloid Leukemia after the Long-term Administration of Low-dose Etoposide for Chronic-type Adult T-cell Leukemia-lymphoma: A Case Report and Literature ReviewIntern Med. 2017;56(14):1879-1884. doi: 10.2169/internalmedicine.56.7763. Epub 2017 Jul 15. 
  7. Kuramitsu M, Sekizuka T, Yamochi T, Firouzi S, Sato T, Umeki K, Sasaki D, Hasegawa H, Kubota R, Sobata R, Matsumoto C, Kaneko N, Momose H, Araki K, Saito M, Nosaka K, Utsunomiya A, Koh KR, Ogata M, Uchimaru K, Iwanaga M, Sagara Y, Yamano Y, Okayama A, Miura K, Satake M, Saito S, Itabashi K, Yamaguchi K, Kuroda M, Watanabe T, Okuma K, Hamaguchi I. Proviral features of human T cell leukemia virus type 1 in carriers with indeterminate western blot results. J Clin Microbiol. 2017 Sep;55(9):2838-2849. doi: 10.1128/JCM.00659-17. Epub 2017 Jul 12. 
  8. Farmanbar A, Firouzi S, Makałowski W, Iwanaga M, Uchimaru K, Utsunomiya A, Watanabe T, Nakai K. Inferring clonal structure in HTLV-1-infected individuals: towards bridging the gap between analysis and visualization. Hum Genomics. 2017  Jul 11;11(1):15. doi: 10.1186/s40246-017-0112-8.
  9. Hirano M, Ohno N, Tanosaki R, Mochizuki M, Ohno-Matsui K, Uchimaru K, Tojo A, Kamoi K. Adult T-cell leukemia cell-induced uveitis: rapid increase in adult T-cell leukemia cells disrupts the blood-ocular barrier. Int J Hematol. 2017 Dec;106(6):842-846. doi: 10.1007/s12185-017-2293-2. Epub 2017 Jul 4.
  10. Yamagishi M, Uchimaru K. Targeting EZH2 in cancer therapy. Curr. Opin. Oncol. 2017. Sep;29(5):375-381. doi: 10.1097/CCO.0000000000000390.
  11. Sanaz Firouzi, Amir Farmanbar, Kenta Nakai, Masako Iwanaga, Kaoru Uchimaru, Atae Utsunomiya, Yutaka Suzuki, Toshiki Watanabe. Clonality of HTLV-1-infected T-cells as a risk indicator for development and progression of adult T-cell leukemia. Blood Advances, 2017. Jun 27;1(15):1195-1205. doi: 10.1182/bloodadvances.2017005900. eCollection 2017 Jun 27.
  12. Fuji S, Yamaguchi T, Inoue Y, Utsunomiya A, Moriuchi Y, Uchimaru K, Owatari S, Miyagi T, Taguchi J, Choi I, Otsuka E, Nakachi S, Yamamoto H, Kurosawa S, Tobinai K, Fukuda T. Development of a modified prognostic index of patients with aggressive adult T-cell leukemia-lymphoma aged 70 years or younger: a possible risk-adapted management strategies including allogeneic transplantation. Haematologica. 2017 Jul;102(7):1258-1265. doi: 10.3324/haematol.2017.164996. Epub 2017 Mar 24.
  13. Tanaka M, Ishikawa S, Ushiku T, Morikawa T, Isagawa T, Yamagishi M, Yamamoto H, Katoh H, Takeshita K, Arita J, Sakamoto Y, Hasegawa K, Kokudo N and Fukayama M. EVI1 modulates oncogenic role of GPC1 in pancreatic carcinogenesis. Oncotarget 8: 99552-99566, 2017
  14. Farmanbar A, Firouzi S, Park SJ, Nakai K, Uchimaru K, Watanabe T. Multidisciplinary insight into clonal expansion of HTLV-1-infected cells in adult T-cell leukemia via modeling by deterministic finite automata coupled with high-throughput sequencing. BMC Med Genomics. 2017 Jan 31;10(1):4. doi: 10.1186/ s12920-016-0241-2.

2016

  1. Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T. Dysregulation of c-Myb Pathway by Aberrant Expression of Proto-oncogene MYB Provides the Basis for Malignancy in Adult T-cell Leukemia/lymphoma Cells. Clin Cancer Res. 22: 5915-5928, 2016
  2. Fuji S, Inoue Y, Utsunomiya A, Moriuchi Y, Uchimaru K, Choi I, Otsuka E, Henzan H, Kato K, Tomoyose T, Yamamoto H, Kurosawa S, Matsuoka K, Yamaguchi T, Fukuda T. Pretransplantation Anti-CCR4 Antibody Mogamulizumab Against Adult T-Cell Leukemia/Lymphoma Is Associated With Significantly Increased Risks of Severe and Corticosteroid-Refractory Graft-Versus-Host Disease, Nonrelapse Mortality, and Overall Mortality. J Clin Oncol. 34: 3426-3433, 2016
  3. Tsunetsugu-Yokota Y, Kobayahi-Ishihara M, Wada Y, Terahara K, Takeyama H, Kawana-Tachikawa A, Tokunaga K, Yamagishi M, Martinez JP, Meyerhans A. Homeostatically Maintained Resting Naive CD4+ T Cells Resist Latent HIV Reactivation. Front. Microbiol. 7: 1944, 2016.
  4. Aoki S, Firouzi S, López Y, Yamochi T, Nakano K, Uchimaru K, Utusnomiya A, Iwanaga M, Watanabe T. Transition of adult T-cell leukemia/lymphoma clones during clinical progression. Int J Hematol. 104: 330-337, 2016. 
  5. Fujikawa D, Nakagawa S, Hori M, Kurokawa N, Soejima A, Nakano K, Yamochi T, Nakashima M, Kobayashi S, Tanaka Y, Iwanaga M, Utsunomiya A, Uchimaru K, Yamagishi M, Watanabe T. Polycomb-dependent epigenetic landscape in adult T-cell leukemia. Blood, 127: 1790-1802, 2016.
  6. Nakano K and Watanabe T. HTLV-1 Rex Tunes the Cellular Environment Favorable for Viral Replication. Viruses, Feb 24;8(3). pii: E58, 2016
  7. Kamoi K, Nagata Y, Mochizuki M, Kobayashi D, Ohno N, Uchimaru K, Tojo A, Ohno-Matsui K. Formation of Segmental Rounded Nodules During Infiltration of Adult T-Cell Leukemia Cells Into the Ocular Mucous Membrane. Cornea, Jan;35(1):137-9, 2016  
  8. Aoki S, Firouzi S, López Y, Yamochi T, Nakano K, Uchimaru K, Utusnomiya A, Iwanaga M, Watanabe T. Transition of adult T-cell leukemia/lymphoma clones during clinical progression. Int J Hematol, 2016 Sep;104(3):330-7. doi: 10.1007/s12185-016-2049-4. Epub 2016 Jul 6.

2015

  1. Kawamata T, Ogawa M, Takei T, Takeda R, Ochi K, Yokoyama K, Fukuyama T, Ohno N, Uchimaru K, Tojo A. An adult case of biphenotypic acute leukemia with t(6;14)(q25;q32). Atlas Genet Cytogenet Oncol Haematol, in press.
  2. Yamagishi M, Katano H, Hishima T, Shimoyama T, Ota Y, Nakano K, Ishida I, Okada S, Watanabe T. Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. Sci. Rep., 5: 17868, 2015
  3. Matsuda Y, Kobayashi-Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M. Epigenetic Heterogeneity in HIV-1 Latency Establishment. Sci. Rep., 5: 7701, 2015. 
  4. Kuramitsu M, Okuma K, Yamagishi M, Yamochi T, Firouzi S, Momose H, Mizukami T, Takizawa K, Araki K, Sugamura K, Yamaguchi K, Watanabe T, Hamaguchi I. Identification of TL-Om1, an Adult T-Cell Leukemia (ATL) Cell Line, as Reference Material for Quantitative PCR for Human T-Lymphotropic Virus 1. J. Clin. Microbiol, 53: 587-596, 2015.
  5. Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru . Advanced human T-cell leukemia virus type 1 carriers and early-stage indolent adult T-cell leukemia-lymphoma are indistinguishable based on CADM1 positivity in flow cytometry. Cancer Sci. 106(5):598-603, 2015. 
  6. Shimada N, Yuji K, Ohno N, Koibuchi T, Oyaizu N, Uchimaru K, Tojo A. Treatment of chronic lymphocytic leukemia with bendamustine in an HIV-infected patient on antiretroviral therapy: a case report and review of the literature. Clin Case Rep. 3(6): 453-60, 2015. 
  7. Kuramitsu M, Okuma K, Yamochi T, Sato T, Sasaki D, Hasegawa H, Umeki K, Kubota R, Sobata R, Matsumoto C, Kaneko N, Naruse I, Yamagishi M, Nakashima M, Momose H, Araki K, Mizukami T, Mizusawa S, Okada Y, Ochiai M, Utsunomiya A, Koh KR, Ogata M, Nosaka K, Uchimaru K, Iwanaga M, Sagara Y, Yamano Y, Satake M, Okayama A, Mochizuki M, Izumo S, Saito S, Itabashi K, Kamihira S, Yamaguchi K, Watanabe T, Hamaguchi I. Standardization of Quantitative PCR for Human T-cell Leukemia Virus Type 1 in Japan: A Collaborative Study. J Clin Microbiol, 53(11):3485-91, 2015. 
  8. Ishigaki T, Zaike Y, Nojima M, Kobayashi S, Ohno N, Uchimaru K, Tojo A, Nakauchi H, Watanabe N. Quantification of adult T-cell leukemia/lymphoma cells using simple four-color flow cytometry. Clin Chem Lab Med. 53(1): 85-93, 2015. 
  9. Konuma T, Kato S, Yuji K, Ohno N, Uchimaru K, Takahashi S, Tojo A. Clearance of blasts from peripheral blood during induction chemotherapy using exponential decay model predicts complete remission and long-term survival in adult acute myeloid leukemia. Int J Lab Hematol. 37(3):e59-62, 2015. 
  10. Ochiya T, Takenaga K, Asagiri M, Nakano K, Satoh H, Watanabe T, Imajoh-Ohmi S, and Endo H. Efficient inhibition of tumor angiogenesis and growth by asynthetic peptide blocking S100A4-methionine aminopeptidase interaction. Mol. Ther. Methods Clin. Dev. 1;2:15008, 2015. 
  11. Tanaka M, Watanabe M, Yokomi I, Matsumoto N, Sudo K, Satoh H, Igarashi T, Seki A, Amano H, Ohura K, Ryu K, Shibata S, Nagayama M, Tanuma J. Establishment of a novel dwarf rat strain: cartilage calcification insufficient (CCI) rats. Exp. Anim. 64(2): 121-128, 2015.

2014

  1. Takahashi R, Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, Nakashima M, Tanaka Y, Uchimaru K, Utsunomiya A, Watanabe T. Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia. Cancer Sci. 105(9):1160-9, 2014. 
  2. Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K. CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-I-infected cells in adult t-cell leukemia/lymphoma. Clin Cancer Res. 20(11):2851-61, 2014.
  3. Konuma T, Kato S, Ooi J, Oiwa-Monna M, Ebihara Y, Mochizuki S, Yuji K, Ohno N, Kawamata T, Jo N, Yokoyama K, Uchimaru K, Tojo A, Takahashi S. Effect of ABO Blood Group Incompatibility on the Outcome of Single-Unit Cord Blood Transplantation after Myeloablative Conditioning. Biol Blood Marrow Transplant. 20(4):577-81, 2014.
  4. Konuma T, Kato S, Ooi J, Oiwa-Monna M, Ebihara Y, Mochizuki S, Yuji K, Ohno N, Kawamata T, Jo N, Yokoyama K, Uchimaru K, Asano S, Tojo A, Takahashi S. Single-Unit Cord Blood Transplantation after Granulocyte Colony-Stimulating Factor-Combined Myeloablative Conditioning for Myeloid Malignancies Not in Remission. Biol Blood Marrow Transplant. 20(3):396-401, 2014.
  5. Konuma T, Kato S, Ooi J, Oiwa-Monna M, Ebihara Y, Mochizuki S, Yuji K, Ohno N, Kawamata T, Jo N, Yokoyama K, Uchimaru K, Tojo A, and Takahashi S. Impact of sex incompatibility on the outcome of single-unit cord blood transplantation for adult patients with hematological malignancies. Bone Marrow Transplant. 49(5):634-9, 2014.
  6. Kawamata T, Ohno N, Sato K, Kobayashi M, Jo N, Yuji K, Tanosaki R,Yamano Y, Tojo A, Uchimaru K. A case of post-transplant adult T-cell leukemia/lymphoma presenting myelopathy similar to but distinct from human T-cell leukemia virus type I (HTLV- I)-associated myelopathy. Springerplus 3:581, 2014.
  7. Firouzi S, López Y, Suzuki Y, Nakai K, Sugano S, Yamochi T, Watanabe T. Development and validation of a new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites. Genome Med. 6(6):46, 2014.
  8. Yamamoto Y, Miyamoto M, Tatsuda D, Kubo M, Nakagama H, Nakamura Y, Satoh H, Matsuda K, Watanabe T, Ohta T. A rare polymorphic variant of NBS1 reduces repair activity and elevates chromosomal instability. Cancer Res74: 3707-3715, 2014.

2013

  1. Ohno N, Kobayashi S, Ishigaki T, Yuji K, Kobayashi M, Sato K, Watanabe N, Tojo A, and Uchimaru K. Loss of CCR4 antigen expression after mogamulizumab therapy in a case of adult T-cell leukaemia-lymphoma. Br J Haematol. 163(5):683-5, 2013.
  2. Asanuma S, Yamagishi M, Kawanami K, Nakano K, Sato-Otsubo A, Muto S, Sanada M, Yamochi T, Kobayashi S, Utsunomiya A, Iwanaga M, Yamaguchi K, Uchimaru K, Ogawa S and Watanabe T. Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth. Cancer Sci. 104(8):1097-106, 2013.
  3. Ishigaki T, Isobe M, Kobayashi S, Yuji K, Ohno N, Watanabe N, Tojo A and Uchimaru K. Development of peripheral T-cell lymphoma not otherwise specified in a HTLV-1 carrier. Int J hematol. 97(5): 667-672, 2013.
  4. Kobayashi S, Tian Y, Ohno N, Yuji K, Ishigaki T, Isobe M, Ohfuchi-Tsuda M, Oyaizu N, Watanabe E, Watanabe N, Tani K, Tojo A and Uchimaru K. The CD3 versus CD7 plot in multicolor flow cytometry reflects progression of disease stage in patients infected with HTLV-I. PLoS One 8, e53728, 2013
  5. Ly BT, Chi HT, Yamagishi M, Kano Y, Hara Y, Nakano K, Sato Y, Watanabe T. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One 8: e66378, 2013. 
  6. Nakano K, Ando T, Yamagishi M, Yokoyama K, Ishida T, Ohsugi T, Tanaka Y, Brighty DW, Watanabe T. Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication. Microbes Infect., 15: 491-505, 2013. 
  7. Togano T, Nakashima M, Watanabe M, Umezawa K, Watanabe T, Higashihara M, Horie R. Synergistic Effect of 5-Azacytidine and NF-κB Inhibitor DHMEQ on Apoptosis Induction in Myeloid Leukemia Cells. Oncol Res.,20(12):571-577, 2013 
  8. Yokomi I, Ogiwara H, Kohno T, Yokota J, Satoh H. Two color fluorescence in situ hybridization analysis of the transfected plasmid DNA in human lung cancer cell line, H1299. Cytologia 78: 121-122, 2013.

2012

  1. Dong Y, Kobayashi S, Tian Y, Ozawa M, Hiramoto T, Izawa K, Bai Y, Soda Y, Sasaki E, Itoh T, Maru Y, Takahashi S, Uchimaru K, Oyaizu N, Tojo A, Kai C and Tani K.  Leukemogenic Fusion Gene (p190 BCR-ABL) Transduction into Hematopoietic Stem/Progenitor Cells in the Common Marmoset. Open Journal of Blood Diseases, 2 1-10, 2012. 
  2. Yamamoto S, Ebihara Y, Mochizuki S, Tsuda M, Yuji K, Uchimaru K, Tojo A, Tsuji K. Acute Lymphoblastic Leukemia with t(1;19)(q23;p13)/TCF3-PBX1 Fusion in an Adult Male with Down Syndrome. Acta Haematol, 128(4):242-243, 2012. 
  3. Yamagishi M, Nakano K, Miyake A, Yamochi T, Kagami Y, Tsutsumi A, Matsuda Y, Sato-Otsubo A, Muto S, Utsunomiya A, Yamaguchi K, Uchimaru K, Ogawa S, and Watanabe T. Polycomb-Mediated Loss of miR-31 Activates NIK-dependent NF-B Pathway in Adult T-cell Leukemia and Other Cancers. Cancer Cell 21(1):121-135, 2012. 
  4. Yamagishi M, Watanabe T. New Paradigm of T cell Signaling: Learning from Malignancies. J. Clin. Cell. Immunol, S12: 007, 2012. 
  5. Yamagishi M, Watanabe T. Molecular Hallmarks of Adult T Cell Leukemia. Front. Microbiol, 3: 334, 2012. 
  6. Kobayashi-Ishihara M, Yamagishi M, Hara T, Matsuda Y, Miyake A, Nakano K, Ishida T, Watanabe T. Identification of a novel HIV-1-encoded antisense RNA, ALe, that can induce prolonged suppression of HIV-1 expression. Retrovirology, 9: 38, 2012. 
  7. Nakano K and Watanabe T. HTLV-1 Rex: the courier of viral messages, making use of the host vehicle. Front. Microbiol, 3:330. 2012.
  8. Watanabe M, Nakano K, Togano T, Nakashima M, Higashihara M, Kadin M E, Watanabe T, and Horie R. Targeted repression of overexpressed CD30 downregulates NF-κB and ERK1/2 pathway in Hodgkin lymphoma cell lines. Oncol. Res., 19; 463-469. 2012 

2011

  1. Uchimaru K. Current problems on the management of HTLV-1 asymptomatic carriers and ATL patients. Rinsho Ketsueki 52(10):1432-1438, 2011.
  2. Tian Y, Kobayashi S, Ohno N, Isobe M, Tsuda M, Zaike Y, Watanabe N, Tani K, Tojo A and Uchimaru K. Leukemic T cells are specifically enriched in a unique CD3dimCD7low subpopulation of CD4+ T cells in acute-type adult T-cell leukemia. Cancer Sci. 102(3) :569-577, 2011. 
  3. Tsuda M, Ebihara Y, Mochizuki S, Uchimaru K, Tojo A and Tsuji K. Reduced dose chemotherapy for acute promyelocytic leukaemia with adult Down syndrome. Br J Haematol, 155(1):130-132, 2011. 
  4. Suzuki K, Ishida T, Yamagishi M, Ahlenstiel C, Swaminathan S, Marks K, Murray D, McCartney EM, Beard MR, Alexander M, Purcell DF, Cooper DA, Watanabe T, Kelleher AD. Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific. RNA Biol, 8: 1035-1046, 2011. 
  5. Yamamoto K, Ishida T, Nakano K, Yamagishi M, Yamochi T, Tanaka Y, Furukawa Y, Nakamura Y, Watanabe T. SMYD3 interacts with HTLV-1 Tax and regulates subcellular localization of Tax. Cancer Sci., 102: 260-266, 2011. 
  6. Zhang X, Hirai M, Cantero S, Ciubotariu R, Dobrila L, Hirsh A, Igura K, Satoh H, Yokomi I, Nishimura T, Yamaguchi S, Yoshimura K, Rubinstein P, Takahashi T.A. Isolation and characterization of mesenchymal stem cells from human umbilical cord blood: Reevaluation of critical factors for successful isolation and high ability to proliferate and differentiate to chondrocytes as compared to mesenchymal stem cells from bone marrow and adipose tissue.  J. Cell. Biochemistry 112: 1206-1218, 2011.
  7. Ogiwara H, Ui A, Otsuka A, Satoh H, Yokomi I, Nakajima S, Yasui A, Yokota J, Kohno T. Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene 30: 2135-2146, 2011. 

2010

  1. Iwanaga M, Watanabe T, Utsunomiya A, Okayama A, Uchimaru K, Koh K, Ogata M, Kikuchi H, Sagara Y, Uozumi K, Mochizuki M, Tsukasaki K, Saburi Y, Yamamura M, Tanaka J, Moriuchi Y, Hino S, Shimeru Kamihira, and Kazunari Yamaguchi. Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan. Blood 116(8):1211-9, 2010. 
  2. Miyake A, Ishida T, Yamagishi M, Hara T, Umezawa K, Watanabe T, Horie R. Inhibition of active HIV-1 replication by NF-kappaB inhibitor DHMEQ. Microbes Infect. 12: 400-408, 2010. 
  3. Nakashima M, Ishii Y, Watanabe M, Togano T, Umezawa K, Higashihara M, Watanabe T, Horie R. The side population, as a precursor of Hodgkin and Reed-Sternberg cells and a target for nuclear factor-κB inhibitors in Hodgkin's lymphoma. Cancer Sci. 101(11):2490-6, 2010. 
  4. Fujino Y, Satoh H, Ohno K, Tsujimoto H. Molecular cytogenetic analysis of feline leukemia virus insertions in cat lymphoid tumor cells. J. Virological Methods. 163: 344-352, 2010.
  5. Yokomi I, Tanaka M, Kobayashi S, Takahashi T, Sudo K, Satoh H. Trisomy of rat chromosome 1 in haematopoietic cell lineages may cause an early-onset of paraplegia. Bull. Nippon Vet. Life Sci. Univ.59: 51-57, 2010. 

2009

  1. Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Hongo E, Uchimaru K, Tojo A, Asano S. Donor cell-derived myelodysplastic syndrome after cord blood transplantation. Bone Marrow Transplant, 43: 429-431, 2009.
  2. Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Kasahara S, Uchimaru K, Iseki T, Tojo A, Asano S. Second myeloabrative alogeneic stem cell tranasplantation (SCT) using cord blood for leukemia relapsed after initial allogeneic SCT. Leuk. Res., 33:840-842, 2009
  3. Konuma T, Takahashi S, Ooi J, Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Kasahara S, Nagamura-Inoue T, Uchimaru K, Iseki T, Tojo A, Yamaguchi T, Asano S. Myeloabrative unrelated cord blood transplantation for acute leukemia patients between 50 and 55 years of age: single institutional retrospective comparison with patients younger than 50 years of age. Ann Hematol, 88(6):581-8, 2009. 
  4. Yamagishi M, Ishida T, Miyake A, Cooper DA, Kelleher AD, Suzuki K, Watanabe T. Retroviral delivery of promoter-targeted shRNA induces long-term silencing of HIV-1 transcription. Microbes Infect. 11: 500-508, 2009. 
  5. Dabaghmanesh N, Matsubara A, Miyake A, Nakano K, Ishida T, Katano H, Horie, R, Umezawa K, and Watanabe T. Transient inhibition of NF-κB by DHMEQ induces cell death of primary effusion lymphoma without HHV-8 reactivation. Cancer Sci., 100; 737–746, 2009.
  6. Togano T, Sasaki M, Watanabe M, Nakashima M, Tsuruo T, Umezawa K, Higashihara M, Watanabe T, Horie R. Induction of oncogene addiction shift to NF-kappaB by camptothecin in solid tumor cells. Biochem Biophys Res Commun. 390(1):60-4, 2009. 
  7. Nakayama J, Yamamoto M, Hayashi K, Satoh H, Bundo K, Kubo M, Goitsuka R, Farrar MA, Kitamura D. BLNK suppresses pre–B-cell leukemogenesis through inhibition of JAK3. Blood 113: 1483-1492, 2009.

2008

  1. Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Uchimaru K, Tojo A. Fatal acute tumor lysis sydrome following intrathecal chemotherapy for acute lymphoblastic leukemia with meningeal involovement. Intern Med., 47: 1987-1988, 2008.
  2. Uchimaru K, Nakamura Y, Tojo A, Watanabe T, Yamaguchi K.  Factors predisposing to HTLV-1 infection in residents of the greater Tokyo Area. Int J Hematol, 88: 565~570, 2008.
  3. Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, Kasahara S, Uchimaru K, Tojo A. Central nervous system leukemia on magnetic resonance imaging. Intern Med. 47: 477, 2008.
  4. Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, Uchimaru K, Iseki T, Tojo A, Asano S. Myeloablative unrelated cord blood transplantation for adult acute myeloid leukemia patients with 11q23 abnormalities. Eur J Hematol, 80: 545-548, 2008.
  5. Watanabe M, Nakashima M, Togano T, Higashihara M, Watanabe T, Umezawa K, Horie R. Identification of the RelA domain responsible for action of a new NF-kappaB inhibitor DHMEQ. Biochem Biophys Res Commun. 376(2):310-4, 2008. 
  6. Yamaguchi N, Oyama T, Ito E, Satoh H, Azuma S, Hayashi M, Shimizu K, Homma R, Yanagisawa Y, Nishikawa A, Kawamura M, Imai J, Ohwada S, Tatsuta K, Inoue J, Semba K, Watanabe S. NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells. Cancer Res. 68: 1881-1888, 2008.

2007

  1. Nakayama S, Nagamura-Inoue T, Yokoyama K, Ohno N, Ooi J, Takahashi S, Uchimaru K, Iseki T, Tojo A. Cytogenetic remissions induced by interferon alpha and imatinib mesylate are immunologically distinct in chronic myeloid leukemia. Int J Hematol, 86: 208-211, 2007.
  2. Kuwabara K, Nishishita T, Morishita M, Oyaizu N, Yamashita S, Kanematsu T, Obara T, Mimura Y, Inoue Y, Kaminishi M, Kaga K, Amino N, Kitaoka M, Ito K, Miyauchi A, Noguchi S, Uchimaru K, Akagawa E, Watanabe N, Takahashi TA, Sato K, Inazawa T, Nakaoka T, Yamashita N. Results of a phase I clinical study using dendritic cell vaccinations for thyroid cancer. Thyroid, 17: 53-8, 2007.
  3. Ohbayashi T, Oikawa K, Yamada K, Nishida-Umehara C, Matsuda Y, Satoh H, Mukai H, Mukai K, Kuroda M. Unscheduled overexpression of human WAPL promotes chromosomal instability. Biochem. Biophys. Res. Commun. 356: 699-704, 2007.
  4. Ito K, Takubo K, Arai F, Satoh H, Matsuoka S, Ohmura M, Naka K, Azuma M, Miyamoto K, Hosokawa K, Ikeda Y, Mak TW, Suda T, Hirao A. Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes. J. Immunol. 178: 103-110, 2007.
  5. Tanaka-Fujita R, Soeno Y, Satoh H, Nakamura Y, Mori S. Human and mouse protein-noncoding snoRNA host genes with dissimilar nucleotide sequences show chromosomal synteny. RNA 13: 811-816, 2007. 

2006

  1. Tomonari A, Takahashi S, Ooi J, Fukuno K, Takasugi K, Tsukada N, Konuma T, Ohno N, Uchimaru K, Iseki T, Tojo A, Asano S. Hemorrhagic Cystitis inAdults after Unrelated Cord Blood Transplantaion: A Single-Institution Experience in Japan. Int. J. Hematol, 84: 268-271, 2006.
  2. Zhang X, Soda Y, Takahashi K, Bai Y, Mitsuru A, Igura K, Satoh H, Yamaguchi S, Tani K, Tojo A, Takahashi TA. Successful immortalization of mesenchymal progenitor cells derived from human placenta and the differentiation abilities of immortalized cells. Biochem. Biophys. Res. Commun. 351: 853-859, 2006.

2005

  1. Konuma T, Uchimaru K, Sekine R, Ohno N, Soda Y, Tomonari A, Ooi J, Nagamura F, Takahashi S, Iseki T, Oyaizu N, Tojo A, Asno S. Atypical hypersensitivity to mosquito bites without natural killer cell proliferative disease in an adult patient. Int J Hematol, Dec;82(5):441-4, 2005.
  2. Tomonari A, Takahashi S, Shimohakamada Y, Ooi J, Takasugi K, Ohno N, Konuma T, Uchimaru K, Tojo A, Odawara T, Nakamura T, Iwamoto A, Asano S. Unrelated cord blood transplantation for a human immunodeficiency virus-I-serepositive patient with acute lymphoblatic leukemia. Bone Marrow Transplant, 36: 261-262, 2005.
  3. Ooi J, Iseki T, Takahashi S, Tomonari A, Takasugi K, Uchiyama M, Konuma T, Fukuno K, Soda Y, Ohno N, Nagamura F, Uchimaru K, Tojo A, Asano S. Unrelated cord blood transplantation after myeloablative conditioning for adult patients with refractory anemia. Int. J. Hematol, 81,424-427, 2005.
  4. Tomonari A, Takahashi S, Ooi J, Iseki T, Takasugi K, Ohno N, Nagamura F, Uchimaru K, Tojo A, Asano S. Human herpesvirus 6 variant B infection is associated with early skin rash and severe graft-versus-host disease in adult patients after unrelated cord blood transplantation. Int. J. Hematol, 81,352-355, 2005.

2004

  1. Cho SG, Shuto Y, Soda Y, Nakazaki Y, Izawa K, Uchiamru K, Takahashi S, Tani K, Tojo A, Asano S. Anti-NK cell treatment induces stale mixed chimerism in MHC-mismatched, T cell-depleted, nonmyeloabrative bone marrow transplatation. Exp. Hematol, 32, 1246-1254, 2004.
  2. Yamada T, Tomonari A, Takahashi A, Ooi J, Iseki T, Shimohakamada Y, Takasugi K, Ohno N, Nagamura F, Uchimaru K, Tojo A, Moriwaki A, Asano S. Unrelated Cord Blood Transplantation With a Reduced Intensity Conditioning Regimen following Autologous Transplantation for Multiple Myeloma. Int. J. Hematol, 80:377-380, 2004.
  3. Takahashi S, Iseki T, Ooi J, Tomonari A, Takasugi K, Shimohakamada Y, Yamada T, Uchimaru K, Tojo A, Shirafuji N, Kodo H, Tani K, Takahashi T, Yamaguchi T, Asano S. Single-institute comparative analysis of unrelated bone marrow transplantation and cord blood transplantation for adult patients with hematological malignancies. Blood, 104:3813-3820, 2004.
  4. Ooi J, Iseki T, Takahashi S, Tomonari A, Takasugi K, Uchiyama Y, Konuma T, Futami T, Nomura A, Nakayama S, Soda Y, Ohno N, Nagamura F, Uchimaru K, Tojo A, Tani K, Asano S. Unrelated cord blood transplantation after myeloablative conditioning in patients over the age of 45 years. Brit. J. Haematol, 126:711-714, 2004.
  5. Tomonari A, Iseki T, Takahashi S, Ooi J, Yamada T, Takasugi K, Nagamura F, Uchimaru K, Tojo A, Asano S. Ganciclovir-related neutropenia after pre-emptive therapy for cytomegalovirus infection: comparison between cord blood and bone marrow transplantation. Ann. Hematol, 83:573-577, 2004.
  6. Harata M, Soda Y, Tani K, Ooi J, Takizawa T, Chen M, Bai Y, Izawa K, Kobayashi S, Tomonari A, Nagamura F, Takahashi S, Uchimaru K, Iseki T, Tsuji T, Takahashi TA, Sugita K, Nakazawa S, Tojo A, Maruyama K, Asano S. CD19-targeting liposomes containing imatinib efficiently kill Philadelphia chromosome-positive acute lymphoblastic leukemia cells. Blood, 104:1442-1449, 2004.
  7. Soda Y, Tani K, Bai Y, Saiki M, Chen M, Izawa K, Kobayashi S, Takahashi S, Uchimaru K, Kuwabara T, Warashina M, Tanabe T, Miyoshi H, Sugita K, Nakazawa S, Tojo A, Taira K, and Asano S. A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood, 104:356-363, 2004.
  8. Tomonari A, Tojo A, Takahashi T, Iseki T, Ooi J, Takahashi S, Nagamura F, Uchimaru K, Asano S. Resolution of Bechet’s disease after HLA-mismatched unrelated cord blood transplantation for myelodysplatic syndrome. Ann Hematol, 83:464-466, 2004.
  9. Morishita M, Uchimaru K, Sato K, Yamashita S, Kanematsu T, Yamashita N. Thyroglobulin-pulsed human monocyte-derived dendritic cells induce CD4+T cell activation. Int. J. Mol. Med., 13: 33-39, 2004.
  10. Yamada T, Suzuki M, Satoh H, Kihara-Negishi F, Nakano H, Oikawa T. Effects of    PU.1-induced mouse calcium-calmodulin-dependent kinase I-like kinase (CKLiK) on apoptosis of murine erythroleukemia cells. Exp. Cell Res. 294: 39-50, 2004. 
  11. Fujiwara M, Tsukamoto Y, Miyazaki A, Moriyama M, Satoh H. Assignment of the murine ankyrin-repeated protein gene (Ankrd2) to mouse chromosome 19C3→D1 and rat chromosome 1q51→q53 by fluorescence in situ hybridization. Cytogenet. Genome Res. 105: 159A, 2004. 
  12. Fujino Y, Ma Z, Satoh H, Mizuno T, Hisasue M, Baba K, Masuda K, Ohno K, Onishi T, Tsujimoto H. Characterization of a newly established nonproducer lymphoma cell line for feline leukemia virus. Vet. Immunol. Immunopathol. 102: 429-439, 2004. 

2003

  1. Tomonari A, Takahashi S, Iseki T, Ooi J, Yamada T, Takasugi K, Shimohakamada Y, Ohno N, Nagamura F, Uchimaru K, Tani K, Tojo A, Asano S. Herpes simplex virus infection in adult patients after unrelated cord blood transplantation: a single institute experience in Japan. Bone Marrow Transplant, 33: 317-320, 2003.
  2. Ooi J, Iseki T, Takahashi S, Tomonari A, Takasugi K, Shomohakamada Y. Yamada T, Ishii K, Ohno N, Nagamura F, Uchimaru K, Tojo A, Asano S. Unrelated cord blood transplantation for adult patients with de novo acute myeloid leukemia. Blood, 103: 489-491, 2003.
  3. Tomonari A, Iseki T, Takahashi S, Ooi J, Takasugi K, Shimohakamada Y, Ohno N, Nagamura F, Uchimaru K, Tani K, Tojo A, Asano S. Varicella-zoster virus infection in adult patients after unrelated cord blood transplantation: a single institute experience in Japan. Br. J. Haematol, 122:802-805, 2003.
  4. Nagamura F, Takahashi T, Takeuchi M, Iseki T, Ooi J, Tomonari A, Uchimaru K, Takahashi S, Tojo A, Tani K, Asano S. Effect of cyclophosphamide on serum cyclosporine levels at the conditioning of hematopoietic stem cell transplantation. Bone Marrow Transplant, 32:1051-1058, 2003.
  5. Nagamura F, Takabe T, Takahashi S, Ohno N, Uchimaru K, Ogami K, Iseki T, Tojo A, Asano S. One allele deletion of the RB1gene in a Case of MDS RA with Del(13)(q12q14): Fluorescence In Situ Hybridization Study of the RB1 gene. Cancer Genet Cytogenet, 146: 77-80, 2003.
  6. Ooi J, Iseki T, Takahashi S, Tomonari A, Ishii K, Takasugi K, Shimohakamada Y, Ohno N, Uchimaru K, Nagamura F, Tojo A, Asano S. Unrelated cord blood transplantation for adult patients with advanced myelodysplastic syndrome. Blood, 101:4711-4713, 2003.
  7. Nagayama H, Sato K, Morishita M, Uchimaru K, Oyaizu N, Inazawa T, Yamasaki T, Enomoto M, Nakaoka T, Nakamura T, Maekawa T, Yamamoto A, Shimada S, Saida T, Kawakami Y, Asano S, Tani K, Takahashi TA, ,Yamashita N. Results of phase I clinical study using autologous tumor-lysate pulsed monocyte-derived mature dendritic cell vaccinations for stage IV malignant melanoma patients combined with low dose interleukin-2, Melanoma Research, 13: 1-10, 2003.

2002

  1. Ooi J, Iseki T, Takahashi S, Tomonari A, Nagayama H, Ishii K, Ito K, Sato H, Takahashi T, Shindo M, Sekine R, Ohno N, Uchimaru K, Nagamura F, Shirafuji N, Tojo A, Tani K, Asano S. A clinical comparison of unrelated cord blood transplantation for adult patients with acute leukemia in complete remission. Br. J. Haematol, 118:140-143, 2002.
  2. Tomonari A, Iseki T, Ooi J, Takahashi S, Ishii K, Takahashi T, Shindo M, Nagamura F, Uchimaru K, Nagayama H, Shirafuji N, Tojo A, Tani K, Asano S. Using related donors other than genotypically HLA-matched siblings in allogeneic hematopoietic stem cell transplantation for hematological disease: a single institution experience in Japan. Int. J. Hematol, 76:354-359, 2002.
  3. Tomanari A, Iseki T, Ooi J, Nagayama H, Sato H, Takahashi T, Ito K, Nagamura F, Uchimaru K, Takahashi S, Shirafuji N, Tojo A, Tani K, Asano S. Second allogeneic hematopoietic stem cell transplantation: outcome of 16 patients in a single institution. Int. J. Hematol, 75:318-323, 2002.

1999

  1. Taniguchi T, Chikatsu N, Takahashi S, Fujita A, Uchimaru K, Asano S, Fujita T, Motokura T. Expression of p16INK4A and p14ARF in hematological malignancies. Leukemia, 13:1760-1769, 1999. 
  2. Taniguchi T, Endo H, Chikatsu N, Uchimaru K, Asano S, Fujita T, Nakahata T, Motokura T. Expression of p21Cip1/ Waf1/ Sdi1 and p27Kip1 cyclin-dependent kainase inhnitors during human hematopoiesis. Blood, 93:4167-4178, 1999.

1998

  1. Taniguchi T, Uchimaru K, Fujita A, Takahashi S, Yoshikawa M, Asano S, Mori S, Fujita T, Motokura T. Cyclin D1 (bcl-1, PRAD1, CCND1) overexpression detected by a simple competitive reverse transcription-polymerase chain reaction assay in lymphoid malignancies. Jpn. J. Cancer Res,, 89:159-166, 1998. 
  2. Uchimaru K, Taniguchi T, Yoshikawa M, Fujinuma H, Fujita T, Motokura T. Growth arrest associated with 12-o-tetradecanoylphorbol-13-acetate-induced hematopoietic differentiation with a defective retinoblastoma tumor suppressor-mediated pathway. Leuk. Res., 22:413-20, 1998.

1997

  1. Uchimaru K, Tanguchi T, Yoshikawa M, Asano S, Arnold A, Fujita T, Motokura T. Detection of cyclin D1(bcl-1, PRAD1) overexpression by a simple competitive reverse transcription-polymerase chain reaction assay in t(11;14)(q13;q32)-bearing B-cell malignancies and/or mantle cell lymphoma. Blood, 89:965-974, 1997.

1996

  1. Uchimaru K, Endo K, Fujinuma H, Zukerberg L, Arnold A, Motokura T. Oncogenic collaboration of the cyclin D1 (PRAD1, bcl-1) gene with a mutated p53 and an activated ras oncogene in neoplastic transformation. Jpn. J. Cancer Res., 87:459-465, 1996.

1995

  1. Kobayashi H, Saito H, Kitano K, Kiyosawa K, Gaun S, Aoki K, Narita A, Watanabe M,  Uchimaru K, Motokura T. Overexpression of the PRAD1 oncogene in a patient with multiple myeloma and t(11;14)(q13;q32). Acta Hematol, 94:199-203, 1995. 
  2. Kobayashi H, Kitano K, Saito H, Aoki K, Narita A, Terada N, Sonoyama M, Uchimaru K, Machii T, Motokura T. Overexpression of the PRAD1 oncogene in a patient with prolymphocytic leukemia with t(11;14)(q13;q32). Cancer Genet. Cytogenet, 84:69-72, 1995. 
  3. Motokura T, Kobayashi Y, Fujita A, Nakamura Y, Taniguchi T, Uchimaru K, Asano S. Clinical significance of serial measurements of the serum levels of soluble interleukin-2 receptor and soluble CD8 in malignant lymphoma. Leuk. Lymph., 16:355-362, 1995. 
  4. Uchimaru K, Motokura T, Takahashi S, Sakurai T, Asano S, Yamashita T. Bone marrow stromal cells produce and respond to activin A: interactions with basic fibroblast growth factor and platelet-derived growth factor. Exp. Heamtol, 23:613-618, 1995.

1992

  1. Takahashi S, Uchimaru K, Harigaya K, Asano S, Yamashita T. Tumor necrosis factor and interleukin-1 induce activin A gene expression in a human bone marrow stromal cell line. Biochem. Biophys. Res. Commun., 188:310-317, 1992.

和文雑誌

  1. 内丸薫「成人T細胞白血病リンパ腫の免疫表現型とnormal counterpart」、血液内科、2017.6 74(6);802-807
  2. 内丸薫「微生物学的検査 ウイルス関連検査 HTLV-1」、Medicia  2015.4 51(1);70-72
  3. 石塚賢治、山野嘉久、宇都宮與、内丸薫「HTLV-1キャリア外来の実態調査」、臨床血液.、2015 Jun;56(6):666-72.
  4. 内丸薫「病気のはなし 成人T細胞白血病(ATL) 」、検査と技術、2014.12 42(13);1370-1375
  5. 内丸薫、東條有伸、中内啓光「成人T細胞白血病(ATL)におけるフローサイトメトリー解析法の確立とその臨床応用 12カラーの病態解析から4カラーの臨床検査まで」、Cytometry Reserch、2014 24(2) 33-3
  6. 鹿島励、根津雅彦、中村孝司、内丸薫(帝京大学第3内科)「非分泌・非産生型多発性骨髄腫と考えられる1例」、日本内科学会雑誌、90:133-135,2001 
  7. 塩島純子、内丸薫、三村治美、津田克彦、小川健、浅井和規、友野寛樹、黒澤進、屋嘉比康治、中村孝司、石田康夫「Intravascular malignant lymphomatosisの1剖検例」、帝京医学雑誌、23:591-600,2000
  8. 折井幸司、小林光、上野真由美、石田文宏、斉藤博、羽田悟、青木和雄、成田厚子、下平滋隆、北野喜良、内丸薫、本倉徹「多彩の臓器浸潤を認めたMantel cell lymphoma.」、臨床血液、38:520-525,1997
  9. 須田一、村山淳一、戸川真一(茨城県立中央病院内科)、松岡正明、高橋俊二、内丸薫(東大4内)「自己免疫性溶血性貧血を呈して発症し,CD7+,CD13+細胞急性白血病に転化した骨髄異形成症候群の1例」、茨城県立病院医学雑誌、10(2):64-72,1992
  10. 舘康雄(茨城県立中央病院内科)、内丸薫(東大4内)、奥村敏之(茨城県立中央’病院放射線科)「背部の筋群に初発し,主として筋組織に病巣を形成した悪性リンパ腫の1症例」、茨城県立病院医学雑誌、 9:82-85,(3)1991
  11. 須田一、内丸薫、山本正克、寺田友彦(茨城県立中央病院)、平本力(茨城県立中央病院皮膚科)、飯野友足(水戸済生会総合病院形成外科)、中山凱夫(筑波大形成外科)、浅井克晏(筑波大内科)、平井周、福田芳郎(順天堂大病理学)「悪性黒色腫、多発性骨髄腫、胃癌が同時に進行し多彩な臨床像を示し、剖検にて、潜伏性前立腺癌も見い出された多重癌の一例」、茨城県立病院医学雑誌、8(4): 165-186,1990
  12. 内丸薫(茨城県立中央病院内科)、高木由紀、福田芳郎(順天堂大学病理学)「発熱、意識障害で発症し、低血糖で推移し死亡した症例」、茨城県立病院医学雑誌、6(2):40-50,1988

和文総説

  1. 山岸誠、鈴木穣、渡邉俊樹、内丸薫「成人T細胞白血病研究におけるシングルセル解析の有用性」、実験医学、37(20)、2019年
  2. 山岸誠、内丸薫「HTLV-1感染細胞の腫瘍化メカニズム」、細胞、51(10)、8-11、2019年
  3. 内丸薫「成人T細胞白血病リンパ腫におけるフローサイトメトリー検査と応用」、臨床病理、 60 (8): 867-875, 2018 
  4. 内丸薫、浜口功「検査UPDATE HTLV-1感染とATLに関する検査」、SRL 宝函、39 (2) :4-11, 2018
  5. 山岸誠「悪性リンパ腫におけるEZH1/EZH2依存性エピゲノム異常と創薬」、血液内科、78(1)、87-92、2018年
  6. 山岸誠「HTLV-1感染細胞におけるゲノム・エピゲノム異常」、医学のあゆみ、267(10)、771-775、2018年
  7. 山岸誠「成人T細胞白血病・リンパ腫のエピゲノム異常と新規EZH1/2阻害剤の開発」、臨床血液、59(4)、432-438、2018年
  8. 内丸薫「HTLV-1関連疾患の疫学」、日本内科学会雑誌、106 (7):1370-1375,2017 
  9. 山岸誠、内丸薫、特集 / 成人T細胞白血病リンパ腫(ATL)研究と診療の進歩「ATL発症における遺伝子翻訳異常」、血液内科、2017
  10. 小林誠一郎、内丸薫「マルチカラーFACSを用いたHTLV-1感染細胞腫瘍化過程の解析」、血液フロンティア、26(4);521-530,2016 
  11. 内丸薫「HTLV-1感染症とATLの研究・診療新時代」、血液フロンティア、26(4);487-490, 2016 
  12. 内丸薫「ATL HTLV-1キャリアと患者の実態」、Skin Cancer、31(2);59-64, 2016  
  13. 山岸誠、渡邉俊樹、特集/成人T細胞白血病(ATL)研究の現状「ATL細胞におけるEZH1/2依存的なエピゲノム制御異常」、血液フロンティア、26(4)、2016年4月 
  14. 内丸薫「HTLV-1キャリア外来の現状と課題」、日本周産期・新生児医学会雑誌、51(1):70-72 (2015).
  15. 内丸薫「成人T細胞白血病」、medicina 、52(4)576-577 (2015).
  16. 内丸薫「成人T細胞白血病(ATL)」、検査と技術、42, 1370-1375, 2014
  17. 内丸薫「わが国におけるHTLV-1キャリアとATL患者に対する相談機能と知識の普及」、血液内科、68(1);58-64, 2014
  18. 内丸薫「成人T細胞白血病・リンパ腫の多彩な肺病変」、血液内科 、66(5); 582-587, 2013
  19. 山岸誠、渡邉俊樹、特集/血液疾患におけるエピゲノム異常と治療「ATL発症におけるエピゲノム解析の進歩 (The State of the Art in Epigenomics of Adult T Cell Leukemia)」、血液内科、66(2)、2013年2月 
  20. 内丸薫「成人T細胞白血病・リンパ腫」、成人病と生活習慣病、 42(6): 743-747, 2012
  21. 山岸誠、Person人と研究「成人T細胞白血病の分子レベルの全体像と、Polycomb- miR-31- NF-kB経路の異常」、Trends in Hematological Malignancies 、4(3):16-19、Dec. 2012.
  22. 山岸誠、渡邉俊樹、特集:microRNAの発現制御の異常と疾患「成人T細胞白血病(ATL)におけるmicroRNAの発現異常」、細胞、44(10):15-22、2012年9月 
  23. 山岸誠、渡邉俊樹、特集:ATLの基礎と臨床「ATL細胞のゲノム エピゲノム異常と発現異常」、細胞、44(8):18-22、2012年7月 
  24. 山岸誠、渡邉俊樹、総説「2.HTLV-1感染症とmiRNA」、ウイルス、62(1):9-18、2012年6月 
  25. 山岸誠、渡邉俊樹、「成人T細胞白血病から明らかになったクロストーク異常とがん」、ライフサイエンス新着論文レビュー、2012年2月 
  26. 内丸薫「HTLV-1キャリア対応・ ATL診療の問題点」、臨床血液、 52(10):1432-1438, 2011
  27. 内丸薫「高齢者の成人T細胞白血病・リンパ腫のマネジメント」、血液内科、62(6): 713-729, 2011
  28. 内丸薫「ビタミンB12吸収試験」、日本臨床(別冊 広範囲血液・尿化学検査,免疫学的検査ーその数値をどう読むか(第6版)(2)、62 : 161-163,2004.
  29. 内丸薫「リツキシマブとCD20」、治療学、36; 1063-1066, 2002.
  30. 内丸薫「患者へのアプローチ-白血病を疑うポイント、疑ったらどうするか」、内科、 84:413-417, 1999.
  31. 内丸薫「ビタミンB12吸収試験」、日本臨床、(別冊血液・尿化学検査、免疫学的検査ーその数値をどう読むか(第5版))、57 : 144-146,1999.
  32. 内丸薫「多クローン性混合型クリオグロブリン血症」、日本臨床、(別冊血液症候群III )、56 : 524--526, 1998.
  33. 内丸薫「単クローン性混合型クリオグロブリン血症」、日本臨床、(別冊血液症候群III )、56 : 521-523, 1998.
  34. 内丸薫「単クローン性単独型クリオグロブリン血症」、日本臨床、(別冊血液症候群III )、56 : 518-520, 1998.
  35. 日高紀子、内丸薫、谷口俊恭「肺臓炎」、Medicina、35 (3): 468-471, 1998
  36. 内丸薫(東大4内)、藤田彰(公立昭和病院血液内科)「成人難治性白血病の治療対策」、Medicina30:646-648,1993
  37. 内丸薫、浅野茂隆(東大4内)「IL-6」、最新医学、 48:687-69,1993

著書(分担執筆)

  1. 山口徹、北原光夫、福井次矢、高木誠、小室一成編「成人T細胞白血病・リンパ腫」、“今日の治療指針” pp707-708、医学書院、東京、2016年 
  2. 幕内雅敏、菅野健太郎、工藤正敏編「白血病・悪性リンパ腫・骨髄腫の消化菅病変」、“今日の消化器疾患治療指針”pp908-909、医学書院、東京、2010年 
  3. 内丸薫「成人T細胞白血病」、“Principles and Practice 血液・造血器・リンパ系“ 千葉滋、長谷川雄一編 pp.288-294, 文光堂、東京、2015
  4. 内丸薫「治療概論 化学療法・放射線療法」、“血液内科学” 浅野茂隆編 中外医学社 東京 pp84-87,1999.
  5. 内丸薫「出血傾向」“この症状をどう診る−主な疾患への各科からのアプローチ” 大原毅、早川浩、藤田敏郎編 pp.329-333 中外医学社 東京 1996
  6. 内丸薫「白血病」、“この症状をどう診る−主な疾患への各科からのアプローチ” 大原毅、早川浩、藤田敏郎編 pp.338-341 中外医学社 東京 1996